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KMID : 0613820050150050834
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Journal of Life Science
2005 Volume.15 No. 5 p.834 ~ p.839
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Effects of Mulberry Fruits Extracts on Serum Lipid Level in Ovariectomized Rats
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Choi Kyung-Ha
Park Mi-Hwa
Kim Mi-Hyang
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Abstract
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The aim of this study was to evaluate the effects of three different mulberry cultivars extracts on serum lipid contents in ovariectomized estrogen-deficient rats. Sprague-Dawley female rats were randomly assigned to the following groups: sham-operated rats (sham), ovariectomized control rats (OVX-control), ovariectomized rats supplemented with 80% ethyl alcohol extracts from various kinds of Tajikistan mulberry (OVX-TM), Korea mulberry (OVX-KM) and China mulberry (OVX-CM) at 200 ㎎/㎏ bw/day, respectively. The mulberry extracts were orally administrated at 1mL per day. The body weights of OVX rats were significantly heavier than the sham-operated rats at all values (p＜0.05). The ovariectomy caused an expected increasing in the levels of serum total cholesterol and triglyceride. The serum HDL-cholesterol level on the OVX-TM, OVX-KM and OVX-CM groups were higher than in the OVX-control group.
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